Contact
Education
PhD, Wright State University
BS, Bowling Green University
Academic Affiliation(s)
Professor, Department of Immunology
Research
Dr. Norris is a Professor in the Department of Immunology and conducts research in immunology and infectious diseases with emphasis on vaccine development, co-morbidities and opportunistic infections associated with HIV infection, chronic immune activation and aging. She has developed a team of investigators and collaborators who provide expertise in all aspects of these studies including veterinary, pulmonary, cardiology, pathology, immunology, radiology, virology and immunology. This team has been successful in establishing the first primate model of Pneumocystispneumonia, chronic obstructive pulmonary disease (COPD) and pulmonary arterial hypertension. Current studies are underway to test the efficacy of Pneumocystis vaccine in pre-clinical models and develop therapeutic interventions to treat inflammation-mediated diseases including diabetes, pulmonary hypertension and COPD.
Lab Personnel
Heather Kling, PhD; Post Doctoral Fellow
Finja Schweitzer, PhD, Post Doctoral Fellow
Rebecca Tarantelli, Research Specialist IV
Allie McManus, Research Specialist IV
Nick Giacobbi, Research Specialist III
ToniAnn Zullo, Research Specialist IV
Michael Bennett Johnston, Research Specialist III
Areas of Interest
Immunology and Infectious Diseases
Publications
Amsellem V, Lipskaia L, Abid S, Poupel L, Houssaini A, Quarck R, Marcos E, Mouraret N, Parpaleix A, Bobe R, Gary-Bobo G, Saker M, Dubois-Randé JL, Gladwin MT, Norris KA, Delcroix M, Combadière C, Adnot S. 2014. CCR5 as a Treatment Target for Pulmonary Arterial Hypertension. Circulation. [Epub ahead of print] | View Abstract
Fitzpatrick ME, Tedrow JR, Hillenbrand ME, Lucht L, Richards T, Norris KA, Zhang Y, Sciurba FC, Kaminski N, Morris A. Microbiol Immunol. 2014. Pneumocystis jirovecii colonization is associated with enhanced Th1 inflammatory gene expression in lungs of humans with chronic obstructive pulmonary disease. Microbiol Immunol. 58(3): 202-11. | View Abstract
Morris A, Norris KA. 2014. Trimethoprim-sulfamethoxazole treatment does not reverse obstructive pulmonary changes in pneumocystis-colonized nonhuman primates with SHIV infection. J Acquir Immune Defic Syndr. 65(4): 381-389.Kling HM, Shipley TW, Guyach S, Tarantelli R, | View Abstract
George MP, Champion HC, Simon M, Guyach S, Tarantelli R, Kling HM, Brower A, Janssen C, Murphy J, Carney JP, Morris A, Gladwin MT, Norris KA. 2013. Physiologic changes in a nonhuman primate model of HIV-associated pulmonary arterial hypertension. Am J Respir Cell Mol Biol. 48(3): 374-381. | View Abstract
Bryan M, Guyach S, Norris KA. 2013. Biolistic DNA vaccination against Trypanosoma infection. Methods Mol Biol. 940: 305-315. | View Abstract
Morris A, Norris KA. 2012. Colonization by Pneumocystis jirovecii and its role in disease. Clin Microbiol Rev. 25(2): 297-317. | View Abstract
Morris A, Gingo M. R, George M. P, Lucht L, Kessinger C, Singh V, Hillenbrand M, Busch M, McMahon D, Norris K. A, Champion H. C, Gladwin M. T, Zhang Y, Steele C, and Sciurba F. C. 2012. Cardiopulmonary function in individuals with HIV infection in the antiretroviral therapy era. AIDS. 26: 731-740. | View Abstract